Kang-Yell Choi Selected Research

phospholipase D1

12/2017	Phospholipase D1 Inhibition Linked to Upregulation of ICAT Blocks Colorectal Cancer Growth Hyperactivated by Wnt/β-Catenin and PI3K/Akt Signaling.
1/2017	Phospholipase D1 Acts through Akt/TopBP1 and RB1 to Regulate the E2F1-Dependent Apoptotic Program in Cancer Cells.
7/2015	Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling β-catenin signaling in cancer-initiating cells.
7/2013	Phospholipase D1 has a pivotal role in interleukin-1β-driven chronic autoimmune arthritis through regulation of NF-κB, hypoxia-inducible factor 1α, and FoxO3a.

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Kang-Yell Choi Research Topics

Disease

42	Neoplasms (Cancer) 01/2023 - 01/2004
25	Colorectal Neoplasms (Colorectal Cancer) 01/2023 - 03/2002
16	Carcinogenesis 01/2019 - 01/2006
9	Wounds and Injuries (Trauma) 01/2023 - 01/2012
6	Alopecia (Baldness) 01/2023 - 01/2012
5	Inflammation (Inflammations) 07/2023 - 01/2006
5	Obesity 11/2022 - 11/2011
4	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 01/2006
4	Osteoporosis 01/2018 - 01/2014
4	Neoplasm Metastasis (Metastasis) 01/2018 - 03/2009
4	Hypoxia (Hypoxemia) 12/2015 - 07/2013
3	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 11/2018 - 04/2012
2	Breast Neoplasms (Breast Cancer) 01/2023 - 08/2013
2	Cicatrix (Scar) 01/2023 - 01/2022
2	Insulin Resistance 11/2022 - 03/2002
2	Residual Neoplasm 10/2020 - 01/2020
2	Stomach Neoplasms (Stomach Cancer) 04/2019 - 01/2016
2	Melanoma (Melanoma, Malignant) 10/2015 - 11/2011
2	Colonic Neoplasms (Colon Cancer) 07/2015 - 04/2012
1	Alzheimer Disease (Alzheimer's Disease) 01/2023
1	Diabetes Mellitus 11/2022
1	Metabolic Diseases (Metabolic Disease) 01/2022
1	Sepsis (Septicemia) 01/2021
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 02/2020
1	Triple Negative Breast Neoplasms 01/2020
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019
1	Osteosarcoma (Osteogenic Sarcoma) 01/2016
1	Peptic Ulcer (Peptic Ulcers) 01/2016
1	Gastritis 01/2016
1	Endometrial Neoplasms (Endometrial Cancer) 08/2015
1	Carcinoma (Carcinomatosis) 07/2015
1	Colitis 07/2015
1	Fibrosis (Cirrhosis) 06/2015
1	Glioblastoma (Glioblastoma Multiforme) 05/2015

Drug/Important Bio-Agent (IBA)

45	CateninsIBA 07/2023 - 01/2011
21	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2007
8	KYA1797KIBA 01/2021 - 01/2016
7	Phospholipase DIBA 12/2015 - 05/2010
7	1-dodecylpyridoxal (PLD)IBA 12/2015 - 05/2010
5	Peptides (Polypeptides)IBA 01/2023 - 11/2017
5	ErbB Receptors (EGF Receptor)IBA 01/2020 - 01/2011
4	ras ProteinsIBA 01/2023 - 08/2015
4	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2018 - 12/2006
4	phospholipase D1IBA 12/2017 - 07/2013
4	beta CateninIBA 05/2010 - 01/2006
3	Calcibiotic Root Canal SealerIBA 11/2018 - 01/2016
3	Cetuximab (Erbitux)FDA Link 11/2018 - 01/2011
3	Panitumumab (Vectibix)FDA Link 11/2018 - 01/2011
3	ZincIBA 12/2003 - 03/2002
2	Valproic Acid (Depakote)FDA LinkGeneric 01/2023 - 06/2015
2	Glycogen Synthase KinasesIBA 01/2023 - 06/2015
2	Fluorouracil (Carac)FDA LinkGeneric 10/2020 - 04/2019
2	LigandsIBA 01/2018 - 03/2002
2	Anabolic AgentsIBA 01/2016 - 01/2014
2	phospholipase D2IBA 11/2015 - 12/2014
2	Oxygen (Dioxygen)IBA 11/2015 - 12/2014
2	Melanins (Melanin)IBA 10/2015 - 11/2011
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 08/2014 - 01/2011
2	Monoclonal AntibodiesIBA 08/2014 - 01/2011
2	CytokinesIBA 07/2013 - 06/2012
2	Complementary DNA (cDNA)IBA 01/2006 - 12/2004
1	Amyloid (Amyloid Fibrils)IBA 01/2023
1	Prostaglandin D2IBA 01/2023
1	Epidermal Growth Factor (EGF)IBA 01/2023
1	ML-265IBA 12/2022
1	Gemcitabine FDA Link 01/2021
1	CardiotoxinsIBA 01/2021
1	angelicae sinensis extract (dang-gui)IBA 02/2020
1	indirubinIBA 02/2020
1	Leucovorin (Folinic Acid)FDA Link 04/2019
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 04/2019
1	Paclitaxel (Taxol)FDA LinkGeneric 04/2019
1	Gefitinib (Iressa)FDA Link 01/2019
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2019
1	Tyrosine Kinase InhibitorsIBA 01/2019
1	Carrier Proteins (Binding Protein)IBA 01/2019
1	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 01/2019
1	Phosphotransferases (Kinase)IBA 01/2018
1	GTP-Binding Proteins (G-Protein)IBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 12/2017
1	Adenosine Triphosphate (ATP)IBA 01/2017
1	Cytotoxins (Cytolysins)IBA 01/2017
1	AntioxidantsIBA 05/2016
1	Parathyroid Hormone (Parathormone)IBA 01/2016
1	rebamipideIBA 01/2016
1	Protective AgentsIBA 01/2016
1	Lipase (Acid Lipase)FDA Link 11/2015
1	Melanocyte-Stimulating Hormones (MSH)IBA 10/2015
1	Estrogens (Estrogen)FDA Link 08/2015
1	rottlerinIBA 08/2015
1	MicroRNAs (MicroRNA)IBA 07/2015
1	AzoxymethaneIBA 07/2015
1	Dextrans (Dextran)FDA Link 07/2015
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 07/2015
1	NNC 55-0396IBA 05/2015

Therapy/Procedure

15	Therapeutics 01/2023 - 01/2006
4	Drug Therapy (Chemotherapy) 10/2020 - 08/2014
2	Aftercare (After-Treatment) 10/2020 - 08/2015
1	Chinese Traditional Medicine (Traditional Chinese Medicine) 02/2020